It's 1998 and over the course of one 12-hour shift at an Arkansas hospital, a junkie nurse, her scheming cousin and a group of black market organ-trading criminals start a heist that could lead to their collective demise.

In 1866, a young doctor is summoned by his uncle to a remote town in the Ozarks only to discover upon his arrival that the utopian paradise is not all that it seems to be.